Simone Saverio Fildi

Simone Saverio Fildi

Biomedical Engineer & Computer Scientist

Biomedical engineer and PhD candidate in AI for health at Università Campus Bio-Medico di Roma. Founder and CTO of globalTone (AI dermoscopy, SaaS & SaMD) and Eureka (AI expert matching), co-founder and CEO of Republic of Minds (white-label research networks). Lead developer of PACY × Google.org and co-author of four peer-reviewed publications (IEEE, Springer). I take AI from research prototype to market-ready product: computer vision, LLM systems, cloud and hardware integration.

Experience

2024 — present

Founder & CTO

globalTone

Medtech startup bringing AI into dermoscopy: a SaaS & SaMD decision support system for early skin cancer detection and patient management. Responsible for the entire technological development — AI model design and training, software and cloud architecture, hardware integration, data pipeline and cybersecurity. Bootstrapped from research prototype to MVP and alpha product; the company is now raising its pre-seed round. Finalist and winner of two Special Prizes at StartCup Lazio 2025.

2026 — present

Founder & CTO

Eureka

AI-powered expert-matching platform connecting companies, researchers and innovators with the right experts for their research and innovation projects. Leading the entire technological development — backend & frontend, AI matching engine, software architecture & infrastructure — and defining the product roadmap. Live in demo version with 15+ early clients.

2026 — present

Co-founder, CEO & CPO

Republic of Minds

White-label community platform for higher education and research: every university, consortium or hospital network gets its own private, branded instance where members find collaborators, start research projects and thesis positions, build startups with co-founders, book mentors and meet at events. Co-founded with Vittorio Colacino; leading the company and the product.

2024 — present

Lead Developer — PACY × Google.org

Università Campus Bio-Medico di Roma

PACY (Pro-Active CYbersecurity) is a generative-AI platform born from the collaboration between Google.org, Università Campus Bio-Medico di Roma and Politecnico di Milano to strengthen the cybersecurity posture of Italian SMEs: an AI virtual expert, trained with industry specialists, guides companies in natural language through incident triage, first containment actions and incident reporting after a cyber attack. Lead developer of the platform from the first line of code, within the CoserityLab research group: I designed and implemented the AI system (Google Gemini and Gemma orchestrated in a multi-agent architecture), led data gathering and API selection, and developed the platform, frontend and backend (Flask). PACY has been acquired by Par-Tec for commercial distribution in Italy.

2024 — present

Teaching Assistant, Tutor & Lecturer

Università Campus Bio-Medico di Roma

Teaching and tutoring for courses across the University's engineering and medical degree programs, supporting lectures, laboratory sessions and student projects:

  • Automation and Safety in Work Environments, M.Sc. in Biomedical Engineering (LM-21), a.y. 2024/25 and 2025/26
  • Digital Twins for Control, Automation and Predictive Maintenance, M.Sc. in Engineering of Intelligent Systems (LM-32), a.y. 2024/25 and 2025/26
  • Dynamics and Control of Chemical Processes, M.Sc. in Chemical Engineering for Sustainable Development (LM-22), a.y. 2025/26
  • Fundamentals of Computer Science, Medicine and Surgery "MedTech" (LM-41), a.y. 2025/26
  • Fundamentals of Computer Science, B.Sc. in Biomedical Engineering (L-8), a.y. 2025/26
2026

Corporate Lecturer

Casagit Salute

Corporate training course "Artificial Intelligence for People and Business": the fundamentals of AI and the myths around it, the European AI Act (requirements and opportunities), practical AI applications for decision-making and operational processes, risk analysis and mitigation, and the ethical use of AI.

2025 — present

Thesis Co-Supervisor

Università Campus Bio-Medico di Roma

Co-supervisor of thesis students across the Biomedical Engineering and the Medicine and Surgery degree programs, on artificial intelligence, computer vision, biomedical instrumentation and IoT:

  • Multi-Device Benchmarking of Lightweight Deep Learning Models for Skin Lesion Segmentation (2026): nine lightweight architectures, including YOLO instance segmentation and encoder-decoder models, on a 5,053-image annotated dataset of smartphone photographs, benchmarked across four edge platforms.
  • 3D Matching Pipeline Between Preoperative CT and Intraoperative Endoscopy for Robot-Assisted Partial Nephrectomy (2026): a markerless monocular pipeline that rebuilds point clouds from endoscopic video (SAM3/MedSAM2 segmentation, metric depth estimation, instrument-based scale correction) and registers them to the CT via multi-start ICP.
  • Multi-User Wearable System Based on LoRa Communication for Man-Down Detection in Operational Teams (2026): GPS, LoRa and inertial sensors to detect falls of first responders outdoors, with a web platform for real-time team monitoring; 92% detection rate on hard-fall tests.
  • Biological Material Transport via UAS: from Payload Design to Regulatory Review (2026): drone transport of pre-transplant blood samples, validated with ENAC, UrbanV and the Lazio Regional Transplant Centre: payload sensors, vibration analysis, biological integrity and a crash-protected container.
  • Standard Dermoscopy vs AI-Integrated Dermoscopy: A 'Patient Safety by Design' Tool for Healthcare Risk Management (2025, Medicine and Surgery): FMECA-based clinical risk analysis of the two workflows, paired with a human-versus-algorithm reader study on ISIC images.

Education

2024 — present

PhD Student

Università Campus Bio-Medico di Roma

National PhD in Artificial Intelligence in Health and Life Sciences. Doctoral research on computer vision and clinical decision support systems for early skin cancer detection and patient management, with an active research collaboration with the Istituto Superiore di Sanità (Italian National Institute of Health). Member of the ARCO Lab (Artificial Intelligence and Computer Systems) and CoserityLab (Complex Systems & Security Lab) research units.

2021 — 2024

M.Sc. in Biomedical Engineering (LM-21)

Università Campus Bio-Medico di Roma

Curriculum in e-Health. Thesis in the area of AI applied to medicine: "AI Dermoscopy through app". Final grade: 110/110 Summa Cum Laude with the Highest Honors for Special Distinction and Academic Career.

2017 — present

Engineering and Data Science Projects

Università Campus Bio-Medico di Roma

Including:

  • AI frameworks applied to medicine: classification, segmentation and decision-support pipelines
  • Full Large Language Model stack: model selection (proprietary vs open-weight, size, cost and latency trade-offs), API integration and local deployment, parameter-efficient fine-tuning (LoRA/QLoRA), prompt engineering and evaluation, RAG and multi-agent architectures
  • Acquisition, processing and analysis of biomedical signals and data
  • IoT solutions: software & hardware sensor interfacing on microcontrollers and signal handling
  • Custom hardware design and custom 3D design
2017 — 2021

B.Sc. in Industrial Engineering (L-9)

Università Campus Bio-Medico di Roma

Thesis in signal processing: "Experimental study and evaluation of tremors". Final grade: 101/110.

2012 — 2017

Scientific High School Diploma

Liceo Scientifico Antonio Labriola, Rome

Publications

  1. 2026

    Investigation of Multi-Site Body Accelerometer and ECG Signals for Fall Detection in Worker Safety Applications

    Pinnelli M., Fildi S.S., Vollero L., Schena E., Setola R., Massaroni C.

    2026 IEEE International Workshop on Metrology for Industry 4.0 & IoT (MetroInd4.0&IoT), IEEE. published

  2. 2025

    PACY: ProActive Cybersecurity for Small and Medium Enterprises

    Fildi S.S., Mannarino G., Peluzzi G., Perone S., Colasante M., Faramondi L., Setola R.

    2025 IEEE International Conference on Cyber Humanities (IEEE-CH), pp. 1–6, IEEE. published

  3. 2026

    Cyber Incident Management Across the Supply Chain: The PACY Approach for Resilience Under NIS2

    Fildi S.S., Mannarino G., Peluzzi G., Perone S., Faramondi L., Setola R.

    Accepted for publication at the European Symposium on Research in Computer Security (ESORICS) 2026, Springer. in press

  4. 2026

    Empirical Characterization of the Ransomware Threat Landscape in the GLAM Sector

    Mannarino G., Perone S., Fildi S.S., Peluzzi G., Guarino S.

    Accepted for publication at the 2026 IEEE International Conference on Cyber Humanities (IEEE-CH), IEEE. in press

  5. 2026

    Benchmarking Small-Scale VLMs for Zero-Shot Dermoscopic Feature Extraction

    Fildi S.S., Colacino V., Cohen M., D'Avenio G., Vollero L.

    Submitted to the IEEE Journal of Biomedical and Health Informatics (JBHI), Special Issue on Emerging AI Technologies and Innovations in Bioinformatics and Health Informatics, March 2026. under review

Projects

2026

derm7p-vlm-bench

Benchmarking small vision-language models for dermoscopy

A benchmark of small (4B-parameter) open-source vision-language models (Gemma, MedGemma and Qwen) for zero-shot dermoscopic feature extraction based on the Seven-Point Checklist, the clinical scoring system used to assess melanoma risk from dermoscopic images.

2026

Archipelago

An evolving ecosystem split across six communicating Docker containers

A teaching project: an original agent-based evolutionary simulator, deliberately split across six Docker containers that have to talk to each other to work at all. It shows, on something alive, the two ways containers interact: over the network and through a shared folder.

2026

imallergicto.it

Free digital allergy cards for travel and restaurants

A web platform to create free digital allergy cards for travel and restaurants, translated into 15 languages, so that people with allergies can explain their dietary restrictions abroad.

2026

vibeBoy

A Game Boy emulator in the VS Code sidebar

A VS Code extension that runs a fully playable Game Boy emulator right in the editor sidebar, built with TypeScript and WasmBoy (WebAssembly). For the minutes spent waiting on a build, the tests or an AI assistant.

Other experiences and achievements

2025 — present

Student Representative & Voting Member, Doctoral School Council

Università Campus Bio-Medico di Roma

Elected representative of doctoral candidates across the four PhD programs of the University, with full voting rights on the council governing the Doctoral School: binding decisions on curriculum changes, research budget allocation and strategic planning.

2025 — present

Student Representative, National PhD in Artificial Intelligence

phd-ai.it

Representing a nationwide network of AI doctoral students across multiple universities, serving as the primary liaison between the student body and the academic board.

2025 — present

Voting Member & Communication Lead, Student Council

Università Campus Bio-Medico di Roma

Voting representative in the University Student Council, participating in binding decisions on campus student life and activities. As Communication Lead, running the Council's official Instagram channel.

2022 — 2025

Student Representative, M.Sc. in Biomedical Engineering

Università Campus Bio-Medico di Roma

Elected representative for the M.Sc. in Biomedical Engineering: primary student advocate in the Degree Program Council on educational quality, exam structure, laboratory activities and student well-being.

2021 — 2024

Class Representative

Università Campus Bio-Medico di Roma

Elected class representative, liaison between students and faculty for teaching activities, exam scheduling and day-to-day academic issues.

2022 — present

Head Organizer, Annual Charity Gala

Università Campus Bio-Medico di Roma

The university's largest philanthropic event. Involved for four consecutive editions and Head Organizer for the past three, managing logistics for 1,500 attendees: partnerships, sponsors, budget and the student committee. The last three editions raised a total of €110,000 for ten charity organizations. Latest edition: Christmas Grand Gala 2025.

May 2025

StartCup Lazio 2025 — Finalist, two Special Prizes

globalTone

Finalist and winner of the Bugnion Special Prize (patent creation) and the ZEST Special Prize (acceleration program access) at StartCup Lazio, the regional business plan competition promoted by Lazio Innova.

2025 & 2026

Global Health Innovation Grand Challenge — Semifinalist

Global Consortium for Innovation and Engineering in Medicine

Semifinalist in two consecutive editions — 2025 (Carle Illinois College of Medicine, University of Illinois Urbana-Champaign) and 2026 (Taipei, Taiwan) — developing engineering solutions for global health.

Skills

AI & Computer Vision

Classification, segmentation and decision-support pipelines applied to medicine, built with PyTorch, TensorFlow and Ultralytics/YOLO.

Full Large Language Model Stack

Model selection, API integration and local deployment, parameter-efficient fine-tuning (LoRA/QLoRA), prompt engineering and evaluation, RAG and multi-agent architectures.

Multiple Expertise

Vertical expertise across software, hardware, IoT and medical integration — full-stack development, custom hardware and 3D design.

Research to Business

Owning technology strategy and product engineering to bring research prototypes to market-ready solutions, from AI models to regulatory-ready platforms.

programming
python, c++, c, matlab, java, typescript, html, latex
ml & computer vision
pytorch, tensorflow, scikit-learn, opencv, ultralytics-yolo
llm & generative ai
huggingface, unsloth, ollama, vllm, langchain, n8n, vector-dbs
mlops, cad & design
docker, wandb, 3d-cad, autocad, autodesk-eagle, figma, adobe-cc
languages
Italian (mother tongue), English (C1 advanced), Spanish (basic)
soft skills
Inquisitiveness, Project leading, Thinking out of the box

Interests and continuous learning

A good share of my time goes into keeping pace with research and technology: papers and preprints, model releases, open-source projects and new tools, tried first-hand rather than just read about. AI is my main field, followed end to end, from the research literature to the engineering that turns it into products people actually use.